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Genetic and Molecular Epidemiology of Multiple Myeloma
Suzanne . Ed(S): Lentzsch
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Description for Genetic and Molecular Epidemiology of Multiple Myeloma
hardcover. This exploration of the role of protein translation in multiple myeloma covers recent advances in oncogenomic research that further our understanding of the disease's molecular pathogenesis, and discusses the emerging technique of epigenetic gene silencing. Editor(s): Lentzsch, Suzanne. Num Pages: 125 pages, biography. BIC Classification: MJCL; MJF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 13. Weight in Grams: 374.
Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of ... Read more
Multiple myeloma is a plasma cell malignancy characterized by complex heterogenous cytogenetic abnormalities that accounts for 1.4% of all cancers, and approximately 10% of hematologic malignancies. The clinical manifestations of multiple myeloma include lytic bone lesions, cytopenia, hypercalcemia, renal dysfunction, hyperviscosity of the blood, immunodeficiency, and peripheral neuropathy. Based on the clinical and genetic data, probably all cases of multiple myeloma arise from an asymptomatic monoclonal gammopathy of unknown significance. The exact mechanism of the transition from MGUS to overt multiple myeloma is still not well understood. Recent oncogenomic studies have further advanced our understanding of the molecular pathogenesis of ... Read more
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer United States
Number of pages
125
Condition
New
Number of Pages
125
Place of Publication
New York, NY, United States
ISBN
9781461446590
SKU
V9781461446590
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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