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Coarse-Grained Modelling of DNA and DNA Self-Assembly
Thomas E. Ouldridge
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Description for Coarse-Grained Modelling of DNA and DNA Self-Assembly
Hardback. This book presents and demonstrates a coarse-grained model of DNA, simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker - it represents the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. Series: Springer Theses. Num Pages: 188 pages, biography. BIC Classification: PHS; PHVN; PNNP; TBN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 15. Weight in Grams: 450.
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
Product Details
Format
Hardback
Publication date
2012
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
188
Condition
New
Series
Springer Theses
Number of Pages
176
Place of Publication
Berlin, Germany
ISBN
9783642305160
SKU
V9783642305160
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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