3%OFF
Stock image for illustration purposes only - book cover, edition or condition may vary.
G Protein-Coupled Receptors: Structure, Signaling, and Physiology
Edited By Sandra Sie
€ 170.40
€ 165.71
FREE Delivery in Ireland
Description for G Protein-Coupled Receptors: Structure, Signaling, and Physiology
hardcover. Comprehensive overview of recent discoveries, the current understanding of the biology of GPCRs and their validity as drug targets. Editor(s): Siehler, Sandra; Milligan, Graeme. Num Pages: 446 pages, 58 b/w illus. 23 tables. BIC Classification: PSBC. Category: (U) Tertiary Education (US: College). Dimension: 253 x 215 x 24. Weight in Grams: 11.
Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically β-adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. ... Read more
Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology of GPCRs, in new assay technologies and drug targeting. The authors take time to detail the importance of the pathophysiological function and drug targeting of GPCRs, specifically β-adrenoceptors in cardiovascular and respiratory diseases, metabotropic glutamate receptors in CNS disorders, S1P receptors in the immune system, and Wnt/Frizzled receptors in osteoporosis. ... Read more
Product Details
Format
Hardback
Publication date
2010
Publisher
Cambridge University Press United Kingdom
Number of pages
446
Condition
New
Number of Pages
446
Place of Publication
Cambridge, United Kingdom
ISBN
9780521112086
SKU
V9780521112086
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-12
About Edited By Sandra Sie
Dr Siehler is a Research Investigator at the Novartis Institute for Biomedical Research in Basel, Switzerland. Dr Siehler is a member of the American Society for Pharmacology and Experimental Therapeutics and the British Pharmacological Society. Dr Milligan is Professor of Molecular Pharmacology at the University of Glasgow. He is actively involved in numerous associations, such as the Biochemical Society and ... Read more
Reviews for G Protein-Coupled Receptors: Structure, Signaling, and Physiology
"The editors of G Protein-Coupled Receptors: Structure, Signaling, and Physiology successfully synthesize decades of research into a well-organized reference textbook. The layout of this text is one of its best features... the strengths of this text would be most appreciated by the structural pharmacologist hoping to gain a comprehensive overview of GPCR biology. The well-outlined chapters balance the abundance and ... Read more