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Chromatin and Disease
. Ed(S): Kundu, Tapas K.; Dasgupta, Dipak
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Description for Chromatin and Disease
Hardback. Different processes such as chromatin assembly, remodeling of chromatin structure coupled to covalent modification of histone and non-histone proteins, chromatin modifying enzymes and DNA-templated phenomena are the potential drug targets for diseases. This work provides an overview of the research activities in these areas. Editor(s): Kundu, Tapas K.; Dasgupta, Dipak. Series: Subcellular Biochemistry. Num Pages: 472 pages, biography. BIC Classification: PSAK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 235 x 155 x 23. Weight in Grams: 951.
It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship ... Read more
It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship ... Read more
Product Details
Format
Hardback
Publication date
2007
Publisher
Springer-Verlag New York Inc. United States
Number of pages
472
Condition
New
Series
Subcellular Biochemistry
Number of Pages
458
Place of Publication
New York, NY, United States
ISBN
9781402054655
SKU
V9781402054655
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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