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DNA Methylation and Cellular Differentiation
James H. Taylor
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Description for DNA Methylation and Cellular Differentiation
paperback. Series: Cell Biology Monographs. Num Pages: 138 pages, biography. BIC Classification: PSB; PSF; UN. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 8. Weight in Grams: 274.
In 1977 I wrote a grant proposal in which I applied to study developmental patterns in enzymatic methylation of DNA in eukaryotes. One part of the proposal was to assay cells at different embryonic developmental stages for maintenance and de novo type methylase activity. With one exception the referees, probably developmental biologists, recommended that the work not be supported because there was no evidence that methylation plays any role in eukaryotic gene regulation. Aside from proving that innovative ideas can seldom be used to successfully compete for grant funds, the skepticism of biologists toward methylation as a regulatory mechanism was, ... Read more
In 1977 I wrote a grant proposal in which I applied to study developmental patterns in enzymatic methylation of DNA in eukaryotes. One part of the proposal was to assay cells at different embryonic developmental stages for maintenance and de novo type methylase activity. With one exception the referees, probably developmental biologists, recommended that the work not be supported because there was no evidence that methylation plays any role in eukaryotic gene regulation. Aside from proving that innovative ideas can seldom be used to successfully compete for grant funds, the skepticism of biologists toward methylation as a regulatory mechanism was, ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer Austria
Number of pages
138
Condition
New
Series
Cell Biology Monographs
Number of Pages
138
Place of Publication
Vienna, Austria
ISBN
9783709187234
SKU
V9783709187234
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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