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DNA Methylation, Epigenetics and Metastasis
Manel . Ed(S): Esteller
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Description for DNA Methylation, Epigenetics and Metastasis
Paperback. Editor(s): Esteller, Manel. Series: Cancer Metastasis - Biology and Treatment. Num Pages: 310 pages, biography. BIC Classification: PSD. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 17. Weight in Grams: 456.
Most of the cancer patients die because the tumoral cells do not "stick" in the original site, but instead detach, invade and disseminate throughout the bloodstream to distal sites, where these transformed cells start to proliferate and destroy again. In the last ten years, researchers have identified a number of important genes involved in these processes, including cadherins, laminins, heparan sulfates, inhibitors of proteases and angiogenesis and many others. The puzzling problem was that few genetic alterations in these genes had been described in human tumors, despite the common finding of down-regulation. CpG island hypermethylation-associated silencing has come to the ... Read more
Most of the cancer patients die because the tumoral cells do not "stick" in the original site, but instead detach, invade and disseminate throughout the bloodstream to distal sites, where these transformed cells start to proliferate and destroy again. In the last ten years, researchers have identified a number of important genes involved in these processes, including cadherins, laminins, heparan sulfates, inhibitors of proteases and angiogenesis and many others. The puzzling problem was that few genetic alterations in these genes had been described in human tumors, despite the common finding of down-regulation. CpG island hypermethylation-associated silencing has come to the ... Read more
Product Details
Format
Paperback
Publication date
2010
Publisher
Springer Netherlands
Number of pages
310
Condition
New
Series
Cancer Metastasis - Biology and Treatment
Number of Pages
310
Place of Publication
Dordrecht, Netherlands
ISBN
9789048169177
SKU
V9789048169177
Shipping Time
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Ref
99-15
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