This book contains revised and extended versions of selected papers from the Fifth International Symposium on Business Modeling and Software Design, BMSD 2015, held in Milan, Italy, in July 2015. The symposium was organized and sponsored by the Interdisciplinary Institute for Collaboration and Research on Enterprise Systems and Technology (IICREST), being co-organized by Politecnico di Milano and technically co-sponsored by BPM-D. Cooperating organizations were Aristotle University of Thessaloniki (AUTH), the U Twente Center for Telematics and Information Technology (CTIT), the BAS Institute of Mathematics and Informatics (IMI), the Dutch Research School for Information and Knowledge Systems (SIKS), and AMAKOTA Ltd.