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Glycocalyx & its Roles in Inflammation & Atherosclerosis
Ye Zeng
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Description for Glycocalyx & its Roles in Inflammation & Atherosclerosis
Paperback. Num Pages: 125 pages. BIC Classification: MBGR; MFCC; PSF. Category: (P) Professional & Vocational. Dimension: 154 x 230 x 11. Weight in Grams: 206.
The major component of glycocalyx, heparan sulfate covalently attaches to proteoglycan core proteins, which is abundant at the cell surface and in the extracellular matrix. Heparan sulfate could provide binding sites on endothelial cells to retain and activate highly diffusible cytokines and inflammatory chemokines to regulate cell functions, such as proliferation and migration. Under physiological and pathological conditions, the remodeling in structure of heparan sulfate including the abnormal expression, and irregular distribution that critically play a fundamental role in inflammation and atherosclerosis, as well as many other diseases was observed. This book aims to integrate a current understanding of the ... Read more
The major component of glycocalyx, heparan sulfate covalently attaches to proteoglycan core proteins, which is abundant at the cell surface and in the extracellular matrix. Heparan sulfate could provide binding sites on endothelial cells to retain and activate highly diffusible cytokines and inflammatory chemokines to regulate cell functions, such as proliferation and migration. Under physiological and pathological conditions, the remodeling in structure of heparan sulfate including the abnormal expression, and irregular distribution that critically play a fundamental role in inflammation and atherosclerosis, as well as many other diseases was observed. This book aims to integrate a current understanding of the ... Read more
Product Details
Format
Paperback
Publication date
2016
Publisher
Nova Science Publishers Inc
Condition
New
Number of Pages
125
Place of Publication
New York, United States
ISBN
9781634858250
SKU
V9781634858250
Shipping Time
Usually ships in 5 to 9 working days
Ref
99-1
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