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DNA Topoisomerase Protocols
. Ed(S): Osheroff, Neil; Bjornsti, Mary-Ann
€ 124.73
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Description for DNA Topoisomerase Protocols
Hardback. This is a collection of protocols for investigating DNA structure, topology, and DNA topoisomerase function. The methods utilize approaches to study changes in DNA topology and DNA structure, assess chromosome structure through FLP-mediated recombination and analyze bacterial nucleoid structure. Editor(s): Osheroff, Neil; Bjornsti, Mary-Ann. Series: Methods in Molecular Biology. Num Pages: 334 pages, biography. BIC Classification: PSAK; PSBZ; PSD. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 665.
Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination. These enzymes further constitute the cellular targets of a number of clinically important antibacterial and anticancer agents. Thus, further studies of DNA topology and DNA topoisomerases are critical to advance our und- standing of the basic biological processes required for cell cycle progression, cell ... Read more
Beginning with the Escherichia coli ? protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes have been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination. These enzymes further constitute the cellular targets of a number of clinically important antibacterial and anticancer agents. Thus, further studies of DNA topology and DNA topoisomerases are critical to advance our und- standing of the basic biological processes required for cell cycle progression, cell ... Read more
Product Details
Format
Hardback
Publication date
2000
Publisher
Humana Press Inc. United States
Number of pages
334
Condition
New
Series
Methods in Molecular Biology
Number of Pages
334
Place of Publication
Totowa, NJ, United States
ISBN
9780896035126
SKU
V9780896035126
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for DNA Topoisomerase Protocols
"This book completes a comprehensive collection of assays, including the weird and wonderful, that can be used to investigate the enzymology and drug inhibition of topoisomerases...I recommend any students about to undertake a PhD degree in this area to buy a copy. Even those who are well versed in the biology of topoisomerases should consider buying both volumes of this ... Read more