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Enzyme-Prodrug Strategies for Cancer Therapy
. Ed(S): Melton, Roger G.; Knox, Richard J.
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Description for Enzyme-Prodrug Strategies for Cancer Therapy
Paperback. Editor(s): Melton, Roger G.; Knox, Richard J. Num Pages: 257 pages, biography. BIC Classification: MJCL; PSB; TBC. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 14. Weight in Grams: 427.
Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours.
This book is the first to describe ADEPT in detail. Each chapter reviews an aspect of the immunology, enzymology, biochemistry, chemistry, and cancer chemotherapy which have ... Read more
Antibody-directed enzyme prodrug therapy (ADEPT) directly addresses the major problem in cancer chemotherapy-its lack of selectivity. Antibody delivery combined with the amplification provided by the enzymatic activation of prodrugs enables selection to be made between tumour and normal tissue. ADEPT offers a novel field of opportunities in the therapy of systemic cancer and may be a major advance for the treatment of solid tumours.
This book is the first to describe ADEPT in detail. Each chapter reviews an aspect of the immunology, enzymology, biochemistry, chemistry, and cancer chemotherapy which have ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag New York Inc. United States
Number of pages
257
Condition
New
Number of Pages
257
Place of Publication
New York, NY, United States
ISBN
9781461371861
SKU
V9781461371861
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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