Michael Domanski is a Professor of Medicine at University Health Network, Peter Munk Cardiovascular Centre and the University of Toronto. He is also the Director of Heart Failure Research and the Patient Inpatient Heart Failure Program and Chairman of the Cardiovascular Clinical Trials Oversight Committee. Professor Domanski has previously held director positions at Trinity Medical Centre, North Dakota and Washington Adventist Hospital. Mandeep Mehra is Professor of Medicine and Head of Cardiology at University of Maryland School of Medicine. He is also the Editor-in-Chief of The Journal of Heart and Lung Transplantation. Professor Mehra has previously been affiliated with Louisiana State University and was the Chief of Ochsner Clinic Foundation's Cardiomyopathy and Heart Transplantation Centre. Marc Alan Pfeffer is a Senior Physician at Brigham and Women's Children Hospial, Boston, Massachusetts and Director of their Cardiovascular Grand Rounds program. He is a recipient of the American Heart Association Clinical Research Prize and is a Senior Associate Editor at Circulation. Professor Pfeffer previously held a position as a Professor of Medicine at Harvard Medical School.