William Small Jr, MD, Professor of Radiation Oncology, Professor and Chair of the Department of Radiation Oncology, Loyola University Chicago Stritch School of Medicine, Chicago, IL, USA Associate Editors Nancy J. Tarbell, MD, Dean for Academic and Clinical Affairs and the C.C. Wang Professor of Radiation Oncology, Harvard Medical School, MA, USA Min Yao, MD, PhD, Department of Radiation Oncology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA Section Editors Minesh Mehta, MD, Jason A. Efstathiou, MD, and Chis Willet, MD Dr Chiu-Chen Wang, Founding Editor of Clinical Radiation Oncology Edited for two successful editions (1988 and 2000) by the eminent physician Dr Chiu-Chen Wang, this book was designed to offer highly practical, application-based comprehensive overview of the biological basis of radiation oncology and the clinical efficacy of radiation therapy. Dr Wang, widely known as C.C. and well known for his ???skilled and no-nonsense methods of dealing with the various types of major organ cancers, passed away in 2005. He was a highly acclaimed leader in the field of radiation oncology based at Harvard Medical School, which established the C.C. Wang Professorship in Radiation Oncology.