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DNA Methylation and Cancer
. Ed(S): Jones, P.A.; Vogt, P. K.
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Description for DNA Methylation and Cancer
Paperback. Editor(s): Jones, P.A.; Vogt, P. K. Series: Current Topics in Microbiology and Immunology. Num Pages: 180 pages, 11 black & white tables, biography. BIC Classification: MJCL; MJCM; PSF. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 10. Weight in Grams: 294.
This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure. The relationship between DNA methylation and genomic imprinting and cancer, and changes in CpG island methylation which occur in aging are discussed. Mouse model systems have played ... Read more
This book is a comprehensive survey of new and exciting developments regarding the role of DNA methylation in human cancer. Issues related to the mutagenicity of 5-methylcytosine and the increase in the interaction of chemical and physical carcinogens with these residues is discussed. The book summarizes the modulation of viral gene expression and the silencing of tumor suppressor genes and illustrates mechanisms by which the methylation signal is translated into altered chromatin structure. The relationship between DNA methylation and genomic imprinting and cancer, and changes in CpG island methylation which occur in aging are discussed. Mouse model systems have played ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
180
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
170
Place of Publication
Berlin, Germany
ISBN
9783642640902
SKU
V9783642640902
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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