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DNA Repair in Cancer Therapy
. Ed(S): Panasci, Lawrence C.; Alaoui-Jamali, Moulay A.
€ 201.41
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Description for DNA Repair in Cancer Therapy
Hardback. Covers the evidence that impaired expression/activity of at least some of the DNA repair proteins account for tumor cell resistance to particular therapeutic agents. This book summarizes reviews covering developments that have potential for translational and clinical applications and focuses on the translational aspect of DNA repair in the clinic. Editor(s): Panasci, Lawrence C.; Alaoui-Jamali, Moulay A. Series: Cancer Drug Discovery and Development. Num Pages: 363 pages, 50 black & white illustrations, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 22. Weight in Grams: 1550.
A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many ... Read more
A comprehensive review of the recent developments in DNA repair that have potential for translational and clinical applications. The authors explain in detail the various mechanisms by which cancer cells can circumvent anticancer therapy and limits its usefulness in patients. They also review the clinical impact of such novel inhibitors of DNA repair mechanisms as methylguanine-DNA-methyltransferase. Also examined are inhibitors of other DNA repair enzymes such as PARP and DNA-PK, now under development and close to clinical trials. The book captures-for both cancer researchers and practicing oncologists dealing with hallmark "relapse" or "drug resistance" phenomena on a daily basis-the many ... Read more
Product Details
Format
Hardback
Publication date
2004
Publisher
Humana Press Inc. United States
Number of pages
363
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
363
Place of Publication
Totowa, NJ, United States
ISBN
9781588292988
SKU
V9781588292988
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for DNA Repair in Cancer Therapy
...gives a comprehensive review of the modern status of the DNA repair field for cancer researchers and clinical practitioners and provides a solid basis for in-depth study of different areas in this field...The book is a timely publication with a significant intended audience that will be served well. The book is well planned, well written, comprehensive, and addresses recent findings ... Read more