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Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson's Disease
Lazaros Constantinos Triarhou
€ 125.98
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Description for Dopaminergic Neuron Transplantation in the Weaver Mouse Model of Parkinson's Disease
Hardback. Marks the culmination of research on the transplantation of dopaminergic neurons in the striatum of the weaver mouse, a neurological mutant characterized by genetically-determined degeneration of midbrain dopamine neurons. This book reviews structural and functional aspects of intrastriatal mesencephalic neuron grafting into the weaver model. Series: Advances in Experimental Medicine and Biology. Num Pages: 148 pages, biography. BIC Classification: MJN; PSAN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 12. Weight in Grams: 910.
Parkinson's disease, a degenerative brain disorder, affects an estimated 0.25-0.50% of the population. Symptoms result from neuronal degeneration in the nigrostriatal dopaminergic pathway and include tremor, rigidity and gradual slow- ness of spontaneous movement. The cause of Parkinson's disease is only partially understood; both environmental factors and a genetic predisposition have been im- plicated in its etiopathogenesis. Neural transplantation is being used experimentally for providing an alternative biological source of dopamine both in animal studies and in experimental clinical trials. This book is the result of 15 years of research on the transplantation of dopaminergic neurons in the striatum of ... Read more
Parkinson's disease, a degenerative brain disorder, affects an estimated 0.25-0.50% of the population. Symptoms result from neuronal degeneration in the nigrostriatal dopaminergic pathway and include tremor, rigidity and gradual slow- ness of spontaneous movement. The cause of Parkinson's disease is only partially understood; both environmental factors and a genetic predisposition have been im- plicated in its etiopathogenesis. Neural transplantation is being used experimentally for providing an alternative biological source of dopamine both in animal studies and in experimental clinical trials. This book is the result of 15 years of research on the transplantation of dopaminergic neurons in the striatum of ... Read more
Product Details
Format
Hardback
Publication date
2003
Publisher
Springer Science+Business Media United States
Number of pages
148
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
148
Place of Publication
, United States
ISBN
9780306474354
SKU
V9780306474354
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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