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Epigenetic Alterations in Oncogenesis
Adam . Ed(S): Karpf
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Description for Epigenetic Alterations in Oncogenesis
hardcover. Epigenetic changes play a major role in various aspects of tumorigenesis. This up-to-date review of the nature and consequences of epigenetic changes in cancer covers every aspect of the topic, including changes in global and promoter-specific DNA methylation. Editor(s): Karpf, Adam. Series: Advances in Experimental Medicine and Biology. Num Pages: 348 pages, biography. BIC Classification: MFN; MJCL. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 707.
The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.
Product Details
Format
Hardback
Publication date
2012
Publisher
Springer United States
Number of pages
348
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
348
Place of Publication
New York, NY, United States
ISBN
9781441999665
SKU
V9781441999665
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Epigenetic Alterations in Oncogenesis
From the reviews: “This well-illustrated book is an excellent source of cutting-edge scientific information on epigenetic marks such as cytosine methylation and cytosine hydroxymethylation, histone tail modifications, histone variants and nucleosome positional information, recognized to play a fundamental role in cancer development and progression. … There are very few books available on this subject. This one will be very ... Read more