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Farnesyltransferase Inhibitors in Cancer Therapy
. Ed(S): Sebti, Sm (Humana Author Usa); Hamilton, Andrew
€ 197.63
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Description for Farnesyltransferase Inhibitors in Cancer Therapy
Hardback. The recent explosion of knowledge gained from genes capable of causing cancer have opened up new avenues for designing anticancer drugs. This volume describes the efforts of several groups in the design and evaluation of these inhibitors. Editor(s): Sebti, SM (Humana author USA); Hamilton, Andrew. Series: Cancer Drug Discovery and Development. Num Pages: 280 pages, biography. BIC Classification: MJCL2; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 17. Weight in Grams: 732.
Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific ... Read more
Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific ... Read more
Product Details
Format
Hardback
Publication date
2000
Publisher
Humana Press Inc. United States
Number of pages
280
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
280
Place of Publication
Totowa, NJ, United States
ISBN
9780896036291
SKU
V9780896036291
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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