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Filaggrin: Basic Science, Epidemiology, Clinical Aspects and Management
Thyssen
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Description for Filaggrin: Basic Science, Epidemiology, Clinical Aspects and Management
Hardcover. Filaggrin Editor(s): Thyssen, Jacob P.; Maibach, Howard I. Num Pages: 373 pages, 78 black & white illustrations, 82 colour illustrations, 30 colour tables, biography. BIC Classification: MFN; MJCM1; MJK. Category: (P) Professional & Vocational. Dimension: 261 x 180 x 22. Weight in Grams: 1012.
Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major ... Read more
Filaggrin gene mutations are common in Europeans and their descendants, as well as in Asians, reaching a prevalence of up to 10%. Filaggrin proteins are crucial for skin homeostasis as their metabolites maintain skin hydration, keep the skin pH low, and provide protection against solar radiation. FLG mutation carriers suffer from dry and scaly skin and have an increased transfer of allergens and chemicals across the epidermis. Moreover, they have 10% higher serum vitamin D levels, potentially affecting the propensity to develop other diseases. FLG loss-of-function mutations represent the strongest risk factor hitherto discovered for atopic dermatitis and are major ... Read more
Product Details
Format
Hardback
Publication date
2014
Publisher
Springer
Condition
New
Number of Pages
373
Place of Publication
Berlin, Germany
ISBN
9783642543784
SKU
V9783642543784
Shipping Time
Usually ships in 5 to 9 working days
Ref
99-3
About Thyssen
Jacob Thyssen has worked in Dermatology for 10 years and holds PhD and DmSci degrees from the University of Copenhagen. He has published 190 articles and 10 book chapters. He has received international awards for his research, including the LEO Pharma Research Foundation for best investigator <45 years in the Nordic countries. His research has focused on dermatitis, allergies, and the skin ... Read more
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