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Guide to Bone Marrow Transplantation
Deeg, H.Joachim (Fred Hutchinson Cancer Research Center); Klingemann, Hans-Georg; Phillips, Gordon L.
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Description for Guide to Bone Marrow Transplantation
Paperback. Num Pages: 192 pages, biography. BIC Classification: MJCL; MJF. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 10. Weight in Grams: 361.
In the late 1940s investigators observed that mice given supralethai doses of total body irradiation were protected by infusion of viable spleen or marrow cells following irradiation, and that this was accomplished by hemopoietic reconsti tution with donor cells as proven using genetic markers. If a similar approach could be applied to humans, it should be possible to treat leukemia patients with any dose of chemoradiotherapy as far as nonmarrow toxicity permitted, and then rescue them by marrow transplantation. Early clinical attempts were gen erally unsuccessful, mostly due to a lack of knowledge of histocompatibility antigens and appropriate supportive care. ... Read more
In the late 1940s investigators observed that mice given supralethai doses of total body irradiation were protected by infusion of viable spleen or marrow cells following irradiation, and that this was accomplished by hemopoietic reconsti tution with donor cells as proven using genetic markers. If a similar approach could be applied to humans, it should be possible to treat leukemia patients with any dose of chemoradiotherapy as far as nonmarrow toxicity permitted, and then rescue them by marrow transplantation. Early clinical attempts were gen erally unsuccessful, mostly due to a lack of knowledge of histocompatibility antigens and appropriate supportive care. ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
192
Condition
New
Number of Pages
192
Place of Publication
Berlin, Germany
ISBN
9783642970795
SKU
V9783642970795
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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