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Histone Deacetylases: Transcriptional Regulation and Other Cellular Functions
Eric . Ed(S): Verdin
€ 239.82
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Description for Histone Deacetylases: Transcriptional Regulation and Other Cellular Functions
hardcover. Summarizes the discoveries in the field of histone acetylation as a key regulatory mechanism for gene expression. This book describes the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. It reviews the structures solved for a number of enzymes. Editor(s): Verdin, Eric. Series: Cancer Drug Discovery and Development. Num Pages: 352 pages, 62 black & white illustrations, 1 colour illustrations, biography. BIC Classification: MBGR; MFGC; MJCL. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 767.
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
Product Details
Format
Hardback
Publication date
2006
Publisher
Humana United States
Number of pages
352
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
352
Place of Publication
Totowa, NJ, United States
ISBN
9781588294999
SKU
V9781588294999
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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