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Human Hybridomas and Monoclonal Antibodies
Edgar . Ed(S): Engleman
€ 131.70
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Description for Human Hybridomas and Monoclonal Antibodies
Paperback. Editor(s): Engleman, Edgar. Num Pages: 526 pages, 115 black & white illustrations, biography. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 29. Weight in Grams: 1045.
Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied. Indeed, production of murine monoclonal antibodies is now considered routine by immunologists and nonimmunologists alike. However, as heterologous proteins, mouse monoclonal antibodies have one major limitation: they are immunogenic in man and, hence, their use in vivo is severely limited. An obvious solution to this problem is to produce human hybridomas with the same techniques used for the production of rodent hybrids. Unfortunately, the history of human hybridomas has been marked ... Read more
Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied. Indeed, production of murine monoclonal antibodies is now considered routine by immunologists and nonimmunologists alike. However, as heterologous proteins, mouse monoclonal antibodies have one major limitation: they are immunogenic in man and, hence, their use in vivo is severely limited. An obvious solution to this problem is to produce human hybridomas with the same techniques used for the production of rodent hybrids. Unfortunately, the history of human hybridomas has been marked ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag New York Inc. United States
Number of pages
526
Condition
New
Number of Pages
526
Place of Publication
New York, NY, United States
ISBN
9781468449518
SKU
V9781468449518
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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