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Immunosuppressant Analogs in Neuroprotection
. Ed(S): Borlongan, Cesario V.; Isacson, Ole; Sanberg, Paul R.
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Description for Immunosuppressant Analogs in Neuroprotection
Paperback. Editor(s): Borlongan, Cesario V.; Isacson, Ole; Sanberg, Paul R. Num Pages: 378 pages, biography. BIC Classification: MJN. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 22. Weight in Grams: 606.
An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory studies with compelling clinical indications for Alzheimer's disease, Huntington's disease, stroke, traumatic brain injury, spinal cord injury, ALS, sciatic nerve injury, and drug addiction. ... Read more
An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory studies with compelling clinical indications for Alzheimer's disease, Huntington's disease, stroke, traumatic brain injury, spinal cord injury, ALS, sciatic nerve injury, and drug addiction. ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Humana Press Inc. United States
Number of pages
378
Condition
New
Number of Pages
378
Place of Publication
Totowa, NJ, United States
ISBN
9781468497427
SKU
V9781468497427
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Immunosuppressant Analogs in Neuroprotection
Forerword by Solomon H. Snyder