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Molecular Aspects of Oxidative Drug Metabolizing Enzymes
. Ed(S): Arinc, Emel; Schenkman, John B.; Hodgson, Ernest
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Description for Molecular Aspects of Oxidative Drug Metabolizing Enzymes
Paperback. Proceedings of the NATO Advanced Study Institute on molecular aspects of drug metabolizing enzymes, held in Kusadasi, Aydin-Turkey, June 20-July 2, 1993 Editor(s): Arinc, Emel; Schenkman, John B.; Hodgson, Ernest. Series: NATO Asi Series / NATO Asi Subseries H:. Num Pages: 614 pages, 10 black & white illustrations, biography. BIC Classification: MJCL; MMG; PSB. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 32. Weight in Grams: 948.
Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.
Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
614
Condition
New
Series
NATO Asi Series / NATO Asi Subseries H:
Number of Pages
614
Place of Publication
Berlin, Germany
ISBN
9783642795305
SKU
V9783642795305
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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