New Therapeutic Targets in Rheumatoid Arthritis
Paul-Peter . Ed(S): Tak
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Description for New Therapeutic Targets in Rheumatoid Arthritis
Hardback. Focuses on therapeutic targets that were identified after TNF blockade. This book discusses the biological rationale in detail, including in vitro work and work in animal models, and where appropriate, results form clinical trials. It is of interest to rheumatologists, immunologists, internists, and investigators in immunology and rheumatology. Editor(s): Tak, Paul-Peter. Series: Progress in Inflammation Research. Num Pages: 228 pages, 9 black & white tables, biography. BIC Classification: MJE. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 18. Weight in Grams: 703.
During the past decades important breakthroughs have been made in the treatment of rheumatoid arthritis (RA). First, the implementation of low-dose methotrexate and other conventional disease-modifying anti-rheumatic drugs was introduced as an effective treatment. Second, it was recognized that early immunomodu- tory treatment is crucial for controlling the disease and its long-term destructive effects more effectively. Parallel advances in research on the pathogenesis of RA and cytokine biology converged in identifying tumor necrosis factor (TNF) as a key factor in inflammation and matrix destruction. The concept arose that elevated TNF concentrations at the sites of inflammation were driving disease pathology, ... Read more
During the past decades important breakthroughs have been made in the treatment of rheumatoid arthritis (RA). First, the implementation of low-dose methotrexate and other conventional disease-modifying anti-rheumatic drugs was introduced as an effective treatment. Second, it was recognized that early immunomodu- tory treatment is crucial for controlling the disease and its long-term destructive effects more effectively. Parallel advances in research on the pathogenesis of RA and cytokine biology converged in identifying tumor necrosis factor (TNF) as a key factor in inflammation and matrix destruction. The concept arose that elevated TNF concentrations at the sites of inflammation were driving disease pathology, ... Read more
Product Details
Format
Hardback
Publication date
2008
Publisher
Birkhauser Verlag AG Switzerland
Number of pages
228
Condition
New
Series
Progress in Inflammation Research
Number of Pages
228
Place of Publication
Basel, Switzerland
ISBN
9783764382377
SKU
V9783764382377
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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