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Protein Expression in Down Syndrome Brain
Gert . Ed(S): Lubec
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Description for Protein Expression in Down Syndrome Brain
Hardback. Presents research work and opinions on Down syndrome. This book focuses on the molecular biology of the Down syndrome brain at the protein level, rather than at nucleic acid level. The studies used fetal brains in which no neurodegeneration was found and characterized proteins by two-dimensional gel electrophoresis and mass spectrometry. Editor(s): Lubec, Gert. Num Pages: 374 pages, biography. BIC Classification: MJCG; MJN; MJTF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 279 x 210 x 22. Weight in Grams: 1183.
When we worked on Down Syndrome brain in the past we have been focus ing on adult brain. This was a major step forwards as most work on Down Syndrome was carried out on fibroblasts or other tissues and, moreover, we introduced proteomics to identify and quantify brain protein expression. We considered evaluation of brain protein expression in Down Syndrome brain by and by more important than gene hunting at the nucleic acid level realiz ing the long unpredictable way from RNA to protein. The availability of fetal samples along with the proteomic appproach stimulated and reinforced studies on Down ... Read more
When we worked on Down Syndrome brain in the past we have been focus ing on adult brain. This was a major step forwards as most work on Down Syndrome was carried out on fibroblasts or other tissues and, moreover, we introduced proteomics to identify and quantify brain protein expression. We considered evaluation of brain protein expression in Down Syndrome brain by and by more important than gene hunting at the nucleic acid level realiz ing the long unpredictable way from RNA to protein. The availability of fetal samples along with the proteomic appproach stimulated and reinforced studies on Down ... Read more
Product Details
Format
Hardback
Publication date
2001
Publisher
Springer Verlag GmbH Austria
Number of pages
374
Condition
New
Number of Pages
374
Place of Publication
Vienna, Austria
ISBN
9783211837320
SKU
V9783211837320
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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