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Sphingolipids and Metabolic Disease
L. Ashley . Ed(S): Cowart
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Description for Sphingolipids and Metabolic Disease
hardcover. This book addresses not only the fundamentals of sphingolipid metabolism and analysis, but also the roles of sphingolipids in these disease processes. It features findings that sphingolipids may regulate cholesterol homeostasis through SREBP and lipid efflux. Editor(s): Cowart, L. Ashley. Series: Advances in Experimental Medicine and Biology. Num Pages: 166 pages, 26 black & white illustrations, 6 black & white tables, biography. BIC Classification: MBGR; MFGM; MJC. Category: (P) Professional & Vocational. Dimension: 263 x 183 x 15. Weight in Grams: 498.
Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological ... Read more
Current thinking holds that obesity derives primarily from overnutrition (though compelling arguments for other mechanisms, like endocrine disruption by environmental pollutants, also gain support from the literature). In animals, overnutrition is initially handled by adipose tissue expansion; however, exhaustion of this route of lipid sequestering results in oversupply of lipid to other tissues including skeletal muscle, heart, liver, and others. Failure of these tissues to clear excess lipids through either metabolism or sequestration into putatively inert triacylglycerols results in perturbation of bioactive lipid metabolism in cells. In particular, aberrant generation of bioactive sphingolipids is implicated in a multitude of pathological ... Read more
Product Details
Format
Hardback
Publication date
2011
Publisher
Springer United States
Number of pages
166
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
148
Place of Publication
New York, NY, United States
ISBN
9781461406495
SKU
V9781461406495
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About L. Ashley . Ed(S): Cowart
L. Ashley Cowart obtained her BS in Biology in 1995 from Furman University in Greenville, South Carolina, and her PhD in Biochemistry in 2001 from Vanderbilt University in Nashville, Tennesee. After postdoctoral work in the laboratory of Dr. Yusuf Hannun, she joined the faculty at the Medical University of South Carolina in Charleston, South Carolina, where she currently holds the ... Read more
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