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Studies on Retinal and Choroidal Disorders
. Ed(S): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College Of Medicine)
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Description for Studies on Retinal and Choroidal Disorders
Paperback. This book examines the role that oxidative and nitrosative stress plays in the physiology and pathophysiology of the retina and choroid. It serves as the ideal guide to understanding the retinal and choroidal cellular mechanisms involved in aging and disease. Editor(s): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College of Medicine). Series: Oxidative Stress in Applied Basic Research and Clinical Practice. Num Pages: 644 pages, 8 colour tables, biography. BIC Classification: MJQ; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 34. Weight in Grams: 997.
Studies on Retinal and Choroidal Disorders examines the role that oxidative and nitrosative stress plays in the complex physiology and pathophysiology of the retina and choroid. Both the basic science researcher and the clinical practitioner can use this book as a guide to the current understanding of retinal and choroidal cellular mechanisms involved in aging and disease. Beginning with a review of oxidative stress and inflammation in the pathoetiology of AMD and a review of the complement system in the retina, the book then takes a detailed look at oxidative stress in lipid metabolism and oxidized lipoproteins in the retina. ... Read more
A detailed look at the Ccl2-/-/Cx3cr1-/- mouse model of AMD follows. Then a detailed examination of the systemic changes in AMD is followed by a discussion of cerium oxide nanoparticle reduction of oxidative stress. Two chapters discuss progenitor cells in the cause and treatment of retinal diseases including AMD and diabetic retinopathy. Natural compounds in the prevention and treatment of retinal diseases are exhaustively presented, followed by a chapter on serotonin 5-HT1A receptor agonists in oxidative stress of the retina. The current anti-VEGF treatment strategies of neovascular AMD are then given. The volume continues with a detailed look at nitric oxide and inducible nitric oxide synthase in retinal vascular disease, an explanation of an in vivo technique of studying the effect of lipid hydroperoxides on circulating leucocytes in the retina, an excellent review of oxidative stress in retinopathy of prematurity, and a look at VEGFinduced oxidative stress in the retinal ganglion cell. The book ends with a detail examination of the role of carotenoids in retinal health and disease. These 31 chapters summarize what is known about oxidative stress in retinal and choroidal disorders. All those involved with degenerative diseases of the eye will find Studies on Retinal and Choroidal Disorders to be illuminating and comprehensive. Show Less
Product Details
Format
Paperback
Publication date
2014
Publisher
Humana Press Inc. United States
Number of pages
644
Condition
New
Series
Oxidative Stress in Applied Basic Research and Clinical Practice
Number of Pages
644
Place of Publication
Totowa, NJ, United States
ISBN
9781627039604
SKU
V9781627039604
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About . Ed(S): Stratton, Robert D.; Hauswirth, William W.; Gardner, Thomas W. (Penn State University College Of Medicine)
Robert D Stratton, MD is the Founder of Erie Retinal Surgery from 1984 to 2008 and past Head of the Division of Retinal Surgery, Department of Ophthalmology, University of Florida School of Medicine from 1980 to 1984 . He is a fellow of the American Board of Ophthalmology, the American Academy of Ophthalmology, and the American College of Surgeons. Dr. Stratton's ... Read more
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