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T Cell Hybridomas
. Ed(S): Boehmer, Harald Von; Haas, W.; Kohler, G.; Melchers, F.; Zeuthen, J.
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Description for T Cell Hybridomas
Paperback. Editor(s): Boehmer, Harald Von; Haas, W.; Kohler, G.; Melchers, F.; Zeuthen, J. Series: Current Topics in Microbiology and Immunology. Num Pages: 276 pages, biography. BIC Classification: MJCL; MJCM; MJCM1; MMFM. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 14. Weight in Grams: 487.
For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2), both of which do not produce Ig, and with Ig producing myelomas (3) or human blood lymphocytes (4). Kohler and Milstein (5) fused a myeloma with spleen cells from immunized mice. Up to 10% of the hybrids obtained secreted antibodies specific for the immunizing antigen. This suggested that plasma cells preferenti ally fused with the myeloma cells, a finding which was of enormous practical value. ... Read more
For more than ten years cell fusion techniques have been applied in studies on various lymphocyte functions. Ig expression was first studied in hybrids obtained by fusing myeloma cells with fibroblasts (1) or lymphomas (2), both of which do not produce Ig, and with Ig producing myelomas (3) or human blood lymphocytes (4). Kohler and Milstein (5) fused a myeloma with spleen cells from immunized mice. Up to 10% of the hybrids obtained secreted antibodies specific for the immunizing antigen. This suggested that plasma cells preferenti ally fused with the myeloma cells, a finding which was of enormous practical value. ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
276
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
264
Place of Publication
Berlin, Germany
ISBN
9783642685880
SKU
V9783642685880
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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