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The Cancer Degradome: Proteases and Cancer Biology
. Ed(S): Edwards, Dylan; Hoyer-Hansen, Gunilla; Blasi, Francesco; Sloane, Bonnie
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Description for The Cancer Degradome: Proteases and Cancer Biology
hardcover. This book covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; and many other relevant subjects, including new approaches to targeting proteolysis for therapy. Editor(s): Edwards, Dylan; Hoyer-Hansen, Gunilla; Blasi, Francesco; Sloane, Bonnie. Num Pages: 926 pages, 41 black & white tables, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 50. Weight in Grams: 1541.
Proteolysis is essential for life. From the breakdown of proteins in food for biosynthesis, through to antigen processing in the immune system, the blood cl- ting cascade, and the hormone-regulated remodelling of female reproductive tissues in adult mammals - proteolysis governs functionality, homeostasis, and fate at the levels of the cell and the entire organism. For the cancer cell, intracellular prote- ysis carried out by caspases and the proteasome must be enlisted and controlled to allow it to escape apoptosis. Functioning on the cancer cell surface or in the extracellular milieu, secreted proteases (primarily metalloproteinases, serine p- teases, and cathepsins) ... Read more
Proteolysis is essential for life. From the breakdown of proteins in food for biosynthesis, through to antigen processing in the immune system, the blood cl- ting cascade, and the hormone-regulated remodelling of female reproductive tissues in adult mammals - proteolysis governs functionality, homeostasis, and fate at the levels of the cell and the entire organism. For the cancer cell, intracellular prote- ysis carried out by caspases and the proteasome must be enlisted and controlled to allow it to escape apoptosis. Functioning on the cancer cell surface or in the extracellular milieu, secreted proteases (primarily metalloproteinases, serine p- teases, and cathepsins) ... Read more
Product Details
Format
Hardback
Publication date
2008
Publisher
Springer United States
Number of pages
926
Condition
New
Number of Pages
926
Place of Publication
New York, NY, United States
ISBN
9780387690568
SKU
V9780387690568
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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