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Tubulin-Binding Agents: Synthetic, Structural and Mechanistic Insights
Teresa . Ed(S): Carlomagno
€ 345.09
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Description for Tubulin-Binding Agents: Synthetic, Structural and Mechanistic Insights
paperback. This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. Editor(s): Carlomagno, Teresa. Series: Topics in Current Chemistry. Num Pages: 342 pages. BIC Classification: MJCL; PNF; PNN; PSB. Category: (G) General (US: Trade). Dimension: 235 x 155 x 18. Weight in Grams: 528.
reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a “time-resolved” picture of the interaction of the drugs ... Read more
reviews. The SAR data are discussed in light of the structural information available for each agent. The second chapter focuses on the total synthesis of the marine sponge-derived polyketide discodermolide. A comprehensive survey of the synthetic chemistry efforts of several groups over a 14-year period is provided together with a compa- son of the different approaches. The third chapter describes a comprehensive study of the mechanisms of activity of microtubules stabilizing drugs. Thermodynamic, kinetic, structural and fu- tional data on microtubules stabilizing drugs are discussed in an interdisciplinary manner to generate a “time-resolved” picture of the interaction of the drugs ... Read more
Product Details
Format
Paperback
Publication date
2014
Publisher
Springer Germany
Number of pages
342
Condition
New
Series
Topics in Current Chemistry
Number of Pages
331
Place of Publication
Berlin, Germany
ISBN
9783642435942
SKU
V9783642435942
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Tubulin-Binding Agents: Synthetic, Structural and Mechanistic Insights