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Checkpoint Controls and Cancer
Axel H. . Ed(S): Schonthal
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Description for Checkpoint Controls and Cancer
Paperback. Editor(s): Schonthal, Axel H. Series: Methods in Molecular Biology. Num Pages: 318 pages, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 17. Weight in Grams: 451.
Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the ... Read more
Intracellular checkpoint controls constitute a network of signal transd- tion pathways that protect cells from external stresses and internal errors. Ext- nal stresses can be generated by the continuous assault of DNA-damaging agents, such as environmental mutagens, ultraviolet (UV) light, ionizing radiation, or the reactive oxygen species that can arise during normal cellular metabolism. In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the ... Read more
Product Details
Format
Paperback
Publication date
2010
Publisher
Humana Press Inc. United States
Number of pages
318
Condition
New
Series
Methods in Molecular Biology
Number of Pages
318
Place of Publication
Totowa, NJ, United States
ISBN
9781617374265
SKU
V9781617374265
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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