Death Receptors in Cancer Therapy
Wafik S. . Ed(S): El-Deiry
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Description for Death Receptors in Cancer Therapy
Hardback. Helps in our understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Editor(s): El-Deiry, Wafik S. Series: Cancer Drug Discovery and Development. Num Pages: 374 pages, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 22. Weight in Grams: 1960.
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression ... Read more
An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression ... Read more
Product Details
Format
Hardback
Publication date
2004
Publisher
Humana Press Inc. United States
Number of pages
374
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
374
Place of Publication
Totowa, NJ, United States
ISBN
9781588291721
SKU
V9781588291721
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Death Receptors in Cancer Therapy
From the reviews: "The book is resourceful for both basic scientists and clinicians, who are interested in developing targeted therapies for cancer. … the book is a valuable tool for researchers as well as to those of us involved in teaching apoptosis to undergraduate and graduate students." (Harikrishna Nakshatri, Leukemia Research, 2005)