Africa can achieve self sufficiency in food production through adoption of innovations in the agriculture sector. Numerous soil fertility and crop production technologies have been generated through research, however, wide adoption has been low. African farmers need better technologies, more sustainable practices, and fertilizers to improve and sustain their crop productivity and to prevent further degradation of agricultural lands. The agricultural sector also needs to be supported by functional institutions and policies that will be able to respond to emerging challenges of globalization and climate change.