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Insulin Resistance and Cancer
I. George . Ed(S): Fantus
€ 195.34
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Description for Insulin Resistance and Cancer
Hardback. This book reviews the epidemiological associations between insulin resistance and cancer, offering in-depth detail of basic concepts of insulin and cancer and how they interact. This is followed by reviews of animal models which support this relationship. Editor(s): Fantus, I. George. Series: Energy Balance and Cancer. Num Pages: 312 pages, 6 black & white tables, biography. BIC Classification: MJCL; MJG; MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 20. Weight in Grams: 631.
This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of the cellular and molecular changes characterizing the insulin resistant state, such as hyperinsulinemia, abnormal metabolism and hormone signaling, and how these interact with various tumor characteristics. For example some tumors present increased quantities of the fetal form of the insulin receptor, unique regulation of oxidative (Krebs’ cycle) metabolism (Warburg effect), as well as mutations in various relevant signaling pathways. Finally, ... Read more
This book reviews the epidemiological associations between insulin resistance and cancer. This is followed by reviews of animal models which support this relationship and provide insight into potential mechanisms. Several chapters then provide detailed examination of the cellular and molecular changes characterizing the insulin resistant state, such as hyperinsulinemia, abnormal metabolism and hormone signaling, and how these interact with various tumor characteristics. For example some tumors present increased quantities of the fetal form of the insulin receptor, unique regulation of oxidative (Krebs’ cycle) metabolism (Warburg effect), as well as mutations in various relevant signaling pathways. Finally, ... Read more
Product Details
Format
Hardback
Publication date
2011
Publisher
Springer-Verlag New York Inc. United States
Number of pages
312
Condition
New
Series
Energy Balance and Cancer
Number of Pages
300
Place of Publication
New York, NY, United States
ISBN
9781441999108
SKU
V9781441999108
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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