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Recent Advances in Transthyretin Evolution, Structure and Biological Functions
. Ed(S): Richardson, Samantha J.; Cody, Vivian
€ 283.30
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Description for Recent Advances in Transthyretin Evolution, Structure and Biological Functions
paperback. The evolution of transthyretin has been extensively investigated, and while the structure of the protein has not changed, its function has changed significantly. This monograph will bring the reader up to date on the latest developments and discoveries. Editor(s): Richardson, Samantha J.; Cody, Vivian. Num Pages: 362 pages. BIC Classification: MFG; MJG; PSBC. Category: (G) General (US: Trade). Dimension: 235 x 155 x 20. Weight in Grams: 581.
Since its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increased about its functions. TTR is synthesised in a wide range of tissues in humans and other eutherian mammals: the liver, choroid plexus (blood- cerebrospinal ?uid barrier), retinal pigment epithelium of the eye, pancreas, intestine and meninges. However, its sites of synthesis are more restricted in other vertebrates. This implies that the number of tissues synthesising TTR during vertebrate evolution has increased, and raises questions about the selection ... Read more
Since its ?rst description in 1942 in both serum and cerebrospinal ?uid, transthyretin (TTR) has had an eventful history, including changes in name from “prealbumin” to “thyroxine-binding prealbumin” to “transthyretin” as knowledge increased about its functions. TTR is synthesised in a wide range of tissues in humans and other eutherian mammals: the liver, choroid plexus (blood- cerebrospinal ?uid barrier), retinal pigment epithelium of the eye, pancreas, intestine and meninges. However, its sites of synthesis are more restricted in other vertebrates. This implies that the number of tissues synthesising TTR during vertebrate evolution has increased, and raises questions about the selection ... Read more
Product Details
Format
Paperback
Publication date
2014
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
362
Condition
New
Number of Pages
362
Place of Publication
Berlin, Germany
ISBN
9783642420719
SKU
V9783642420719
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Recent Advances in Transthyretin Evolution, Structure and Biological Functions
From the reviews: “Transthyretin (TTR) is a relatively abundant thyroid hormone carrier protein found in the blood of vertebrates. … The authors of the book Recent Advances in Transthyretin Evolution, Structure and Biological Functions have produced a comprehensive reference text that does much to reconcile the evolutionary biology, structure-function relationships and pathophysiology of this remarkable protein. … In summary, ... Read more