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Selective Estrogen Receptor Modulators
Manni, Andrea; Verderame, Michael
€ 205.04
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Description for Selective Estrogen Receptor Modulators
Hardback. Presents information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. This book focuses on the mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity. Series: Contemporary Endocrinology. Num Pages: 384 pages, biography. BIC Classification: MJG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 22. Weight in Grams: 888.
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment ... Read more
Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs. The basic science chapters of the book focus-with an eye to the development of the ideal SERM-on the complex mechanisms of estrogen action, including ligand-dependent conformational changes in alpha and beta, and the recruitment of co-activators and co-repressors which modulate the estrogen receptor transcriptional activity and contribute to its crosstalk with growth factor signaling. The clinical presentation reviews the data accumulated on currently available SERMs, primarily tamoxifen and raloxifene, in cancer treatment ... Read more
Product Details
Format
Hardback
Publication date
2002
Publisher
Humana Press Inc. United States
Number of pages
384
Condition
New
Series
Contemporary Endocrinology
Number of Pages
374
Place of Publication
Totowa, NJ, United States
ISBN
9780896039124
SKU
V9780896039124
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Selective Estrogen Receptor Modulators
"...this book is densely packed with data will be valuable for investigators in the field as well as those new to this area. There are many details of interest to the molecular endocrinologist. The clinical information is also intriguing for the clinician who needs to know how to apply the SERMs in the management of postmenopausal problems." - Oncology ... Read more