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Description for Drug-Like Properties
Hardcover. .
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and ... Read more
Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and ... Read more
Product Details
Publisher
Elsevier Science Publishing Co Inc United States
Number of pages
580
Format
Hardback
Publication date
2016
Condition
New
Weight
1825g
Number of Pages
580
Place of Publication
San Diego, United States
ISBN
9780128010761
SKU
V9780128010761
Shipping Time
Usually ships in 4 to 8 working days
Ref
99-8
About Li Di
Li Di is an Associate Research Fellow at Pfizer, USA
Reviews for Drug-Like Properties