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Mitochondrial DNA, Mitochondria, Disease and Stem Cells
St. John Justin C.
€ 132.33
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Description for Mitochondrial DNA, Mitochondria, Disease and Stem Cells
Paperback. This book shows how the mitochondrial genome is transmitted, segregated and inherited. Opens by describing mtDNA mutations and deletions and showing how these impact the offspring's well-being, covers mtDNA transmission and discusses transmittal and adaptation. Editor(s): John, Justin C. Series: Stem Cell Biology and Regenerative Medicine. Num Pages: 200 pages, 5 black & white tables, biography. BIC Classification: MBGR; PSAK; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 11. Weight in Grams: 314.
This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease. The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be ... Read more
This volume investigates how the mitochondrial genome is transmitted, segregated, and inherited. It starts by describing mtDNA mutations and deletions and how these impact on the offspring’s well-being. It progresses to discuss how mutations to the mtDNA-nuclear-encoded transcription, replication and translational factors lead to mtDNA-depletion syndromes and how these affect cellular function and lead to the pathology of human mitochondrial disease. It also highlights the importance of the mitochondrial assembly factors and how mutations to these can lead to mitochondrial disease. The reader is then introduced to how mtDNA is transmitted through the oocyte and how stem cells can be ... Read more
Product Details
Publisher
Humana Press Inc. United States
Number of pages
200
Format
Paperback
Publication date
2014
Series
Stem Cell Biology and Regenerative Medicine
Condition
New
Number of Pages
190
Place of Publication
Totowa, NJ, United States
ISBN
9781627038676
SKU
V9781627038676
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About St. John Justin C.
Professor Justin St. John was awarded his PhD in 1999. In 2000, he was awarded a Mellon Fellowship at the Oregon National Primate Research Center, Oregon, USA. His achievements as an early career scientist led to his rapid promotion to the position of Professor at the University of Warwick (2007). Whilst in the UK, he was funded by the Medical ... Read more
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