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The Ubiquitin System in Health and Disease
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Description for The Ubiquitin System in Health and Disease
Hardback. The ubiquitin system plays an essential role in numerous cellular processes by controlling protein stability and function. An understanding of the mechanisms governing these processes is likely to allow the identification of novel targets for pharmacological intervention. This work covers the developments in this field. Series: Ernst Schering Foundation Symposium Proceedings. Num Pages: 191 pages, 7 black & white illustrations, 32 colour illustrations, biography. BIC Classification: MBGR; MF. Category: (P) Professional & Vocational. Dimension: 210 x 130 x 15. Weight in Grams: 479.
The ubiquitin system has two major functions in eukaryotic cells: it r- ulates protein degradation, which is essential for normal cellular fu- tion and for the removal of potentially harmful, damaged, or misfolded proteins, and it controls protein activity by regulating protein-protein interactions and subcellullar localization. The ubiquitin system is thus involved in processes as diverse as cell cycle progression, signal tra- duction, gene transcription, and DNA repair. Not surprisingly, defects in the ubiquitin system have been linked with numerous diseases such as cancer, in?ammation, central nervous system disorders, and metabolic dysfunction. Ubiquitin is a highly conserved 76-amino acid protein ... Read more
The ubiquitin system has two major functions in eukaryotic cells: it r- ulates protein degradation, which is essential for normal cellular fu- tion and for the removal of potentially harmful, damaged, or misfolded proteins, and it controls protein activity by regulating protein-protein interactions and subcellullar localization. The ubiquitin system is thus involved in processes as diverse as cell cycle progression, signal tra- duction, gene transcription, and DNA repair. Not surprisingly, defects in the ubiquitin system have been linked with numerous diseases such as cancer, in?ammation, central nervous system disorders, and metabolic dysfunction. Ubiquitin is a highly conserved 76-amino acid protein ... Read more
Product Details
Format
Hardback
Publication date
2008
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
191
Condition
New
Series
Ernst Schering Foundation Symposium Proceedings
Number of Pages
191
Place of Publication
Berlin, Germany
ISBN
9783540851066
SKU
V9783540851066
Shipping Time
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Ref
99-15
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