Batch Effects and Noise in Microarray Experiments: Sources and Solutions
Andreas Scherer
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Description for Batch Effects and Noise in Microarray Experiments: Sources and Solutions
Hardcover. Batch effects and experimental shift are major sources for noise in a microarray dataset. Their effect on gene expression profiling has been largely ignored until now. This book provides a valuable insight into the nature of batch effects, providing guidance on possible ways of dealing with it and illustrating ways of keeping it to a minimum. Series: Wiley Series in Probability and Statistics. Num Pages: 272 pages, Illustrations. BIC Classification: MBNS; MFN. Category: (P) Professional & Vocational. Dimension: 253 x 175 x 21. Weight in Grams: 618.
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information.
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information.
Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized.
Key Features:
- A thorough introduction to Batch Effects and ... Read more
- A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data.
- An extensive overview of current standardization initiatives.
- All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced.
An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.
Show LessProduct Details
Format
Hardback
Publication date
2009
Publisher
John Wiley & Sons Inc United Kingdom
Number of pages
272
Condition
New
Series
Wiley Series in Probability and Statistics
Number of Pages
288
Place of Publication
New York, United States
ISBN
9780470741382
SKU
V9780470741382
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50
About Andreas Scherer
Andreas Scherer studied biology in Cologne, Germany, and Freiburg, Germany, and received his Ph.D. for his studies in the fields of genetics, developmental biology, and microbiology. Following a postdoctoral position at UT Southwestern Medical Center in Dallas, TX, he worked for many years in pharmaceutical industry in various positions in the field of experimental and statistical genomics biomarker discovery. In ... Read more
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