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PI3K-mTOR in Cancer and Cancer Therapy
. Ed(S): Dey, Nandini; De, Pradip; Leyland-Jones, Brian
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Description for PI3K-mTOR in Cancer and Cancer Therapy
Hardback. Editor(s): Dey, Nandini; De, Pradip; Leyland-Jones, Brian. Series: Cancer Drug Discovery and Development. Num Pages: 318 pages, 31 colour illustrations, 28 colour tables, biography. BIC Classification: MBGR; MFCC; MJCL; MMG. Category: (G) General (US: Trade). Dimension: 235 x 155 x 19. Weight in Grams: 643.
In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority of solid ... Read more
In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority of solid ... Read more
Product Details
Format
Hardback
Publication date
2016
Publisher
Springer International Publishing AG Switzerland
Number of pages
318
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
294
Place of Publication
Basel, Switzerland
ISBN
9783319342092
SKU
V9783319342092
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About . Ed(S): Dey, Nandini; De, Pradip; Leyland-Jones, Brian
Nandini Dey, M.S., Ph.D., is a Senior Scientist Head of Cancer Biology, Avera Cancer Institute Center for Precision Oncology. She is also Assistant Professor of the Department of Internal Medicine at The University of South Dakota Sanford School of Medicine. Dey has more than 20 years of experience in translational research and has authored or co-authored more than 80 publications.< ... Read more
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