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36th Hemophilia Symposium Hamburg 2005
. Ed(S): Scharrer, Inge; Schramm, Wolfgang
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Description for 36th Hemophilia Symposium Hamburg 2005
Paperback. Editor(s): Scharrer, Inge; Schramm, Wolfgang. Num Pages: 319 pages, 51 black & white tables, biography. BIC Classification: MJF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 13. Weight in Grams: 545.
About 31% of the patients with a factor VIII replacement therapy develop a factor VIII inhibitor.From these are 23% low-responder (< 5BE) and 77% high-responder (> 5BE) [8].In the case of severe hemophilia B,about 10.5% of the patients develop inhibitory antibodies [9]. Anti-factor VIII-antibodies are also seen in 15-78% healthy people without hemophilia [7, 17, 19]. Lacroix-Desmazes et al. [10, 11] showed anti-idiotypic antibodies neutralizing the inhibitory activity of the an- factor VIII antibodies in healthy people. Well-known predisposing factors for inhibitor formation are genetic features of factor VIII,which include large deletions,nonsense mutations or intrachromosomal recombinations [5, 23].Also, ethnic groups ... Read more
About 31% of the patients with a factor VIII replacement therapy develop a factor VIII inhibitor.From these are 23% low-responder (< 5BE) and 77% high-responder (> 5BE) [8].In the case of severe hemophilia B,about 10.5% of the patients develop inhibitory antibodies [9]. Anti-factor VIII-antibodies are also seen in 15-78% healthy people without hemophilia [7, 17, 19]. Lacroix-Desmazes et al. [10, 11] showed anti-idiotypic antibodies neutralizing the inhibitory activity of the an- factor VIII antibodies in healthy people. Well-known predisposing factors for inhibitor formation are genetic features of factor VIII,which include large deletions,nonsense mutations or intrachromosomal recombinations [5, 23].Also, ethnic groups ... Read more
Product Details
Format
Paperback
Publication date
2006
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
319
Condition
New
Number of Pages
319
Place of Publication
Berlin, Germany
ISBN
9783540367147
SKU
V9783540367147
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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