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Analyzing T Cell Responses
. Ed(S): Nagorsen, Dirk; Marincola, F.M. (National Institutes Of Health)
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Description for Analyzing T Cell Responses
Hardback. Offers an assessment of the various assays that have been used for the monitoring of antigen-specific immune responses. This book emphasizes a global approach to the analysis of T cell mediated target/host interactions at the systemic and the peripheral level when such interactions are supposed to occur. Editor(s): Nagorsen, Dirk; Marincola, F.M. (National Institutes of Health). Num Pages: 314 pages, biography. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 232 x 156 x 27. Weight in Grams: 800.
Active specific immunotherapy is a promising but investigational modality in the management of cancer patients. Currently, several different cancer vaccine formulations such as peptides, proteins, antigen-pulsed dendritic cells, whole tumor cells, etc. in combination with various adjuvants and carriers are being evaluated in clinical trials (1-3). To determine the optimal cancer vaccine strategy, a surrogate immunological end-point that correlates with clinical outcome needs to be defined, since it would facilitate the rapid comparison of these various formulations. Traditional immunological assays such as ELISA, proliferation and cytotoxicity assays can detect immune responses in vaccinated patients but are not quantitative. In contrast, ... Read more
Active specific immunotherapy is a promising but investigational modality in the management of cancer patients. Currently, several different cancer vaccine formulations such as peptides, proteins, antigen-pulsed dendritic cells, whole tumor cells, etc. in combination with various adjuvants and carriers are being evaluated in clinical trials (1-3). To determine the optimal cancer vaccine strategy, a surrogate immunological end-point that correlates with clinical outcome needs to be defined, since it would facilitate the rapid comparison of these various formulations. Traditional immunological assays such as ELISA, proliferation and cytotoxicity assays can detect immune responses in vaccinated patients but are not quantitative. In contrast, ... Read more
Product Details
Format
Hardback
Publication date
2005
Publisher
Springer-Verlag New York Inc. United States
Number of pages
314
Condition
New
Number of Pages
314
Place of Publication
New York, NY, United States
ISBN
9781402036224
SKU
V9781402036224
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Analyzing T Cell Responses
From the reviews of the first edition: "This book represents the first comprehensive description, and evaluation of the most important assays utilized to monitor immune responses against tumor associated antigens. … Specifically tailored to the needs of clinical researchers, basic science investigators, and biotechnology innovators, this book provides information that is both sufficiently detailed and ... Read more