Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies
Zeggini Eleftheria
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Description for Assessing Rare Variation in Complex Traits: Design and Analysis of Genetic Studies
Hardcover. Editor(s): Zeggini, Eleftheria; Morris, Andrew. Num Pages: 261 pages, 10 black & white illustrations, 26 colour illustrations, 14 black & white tables, biograp. BIC Classification: MBGR; MFN; PBT. Category: (P) Professional & Vocational. Dimension: 166 x 324 x 19. Weight in Grams: 554.
This book is unique in covering a wide range of design and analysis issues in genetic studies of rare variants, taking advantage of collaboration of the editors with many experts in the field through large-scale international consortia including the UK10K Project, GO-T2D and T2D-GENES. Chapters provide details of state-of-the-art methodology for rare variant detection and calling, imputation and analysis in samples of unrelated individuals and families. The book also covers analytical issues associated with the study of rare variants, such as the impact of fine-scale population structure, and with combining information on rare variants across studies in a meta-analysis framework.
Genetic ... Read moreProduct Details
Format
Hardback
Publication date
2015
Publisher
Springer
Condition
New
Number of Pages
263
Place of Publication
New York, United States
ISBN
9781493928231
SKU
V9781493928231
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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