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BLyS Ligands and Receptors
Michael P. . Ed(S): Cancro
€ 239.40
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Description for BLyS Ligands and Receptors
Hardback. This volume covers both the basic and translational/clinical aspects of this molecular family, focusing on its role in the differentiation, selection, and regulation of primary and antigen-experienced B cells. In addition, clinical aspects are detailed. Editor(s): Cancro, Michael P. Series: Contemporary Immunology. Num Pages: 295 pages, 19 black & white illustrations, 21 colour illustrations, 12 black & white tables, biograp. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 239 x 161 x 26. Weight in Grams: 648.
Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis. Previously, the B-cell antigen receptor (BCR) was viewed as the sole mediator of these parameters, in which BCR signals were not only dominant but were also linearly related to consequent outcomes. However, appreciating that BLyS signaling is an equal partner in establishing and maintaining B-cell pools in- cated that additional regulatory complexity – apparently based on population density and homeostatic demands – had to be included in models of B-cell behavior. This ... Read more
Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis. Previously, the B-cell antigen receptor (BCR) was viewed as the sole mediator of these parameters, in which BCR signals were not only dominant but were also linearly related to consequent outcomes. However, appreciating that BLyS signaling is an equal partner in establishing and maintaining B-cell pools in- cated that additional regulatory complexity – apparently based on population density and homeostatic demands – had to be included in models of B-cell behavior. This ... Read more
Product Details
Format
Hardback
Publication date
2009
Publisher
Humana Press Inc. United States
Number of pages
295
Condition
New
Series
Contemporary Immunology
Number of Pages
284
Place of Publication
Totowa, NJ, United States
ISBN
9781603270120
SKU
V9781603270120
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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