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Camptothecins in Cancer Therapy
Val R. . Ed(S): Adams
€ 272.55
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Description for Camptothecins in Cancer Therapy
Paperback. Editor(s): Adams, Val R. Series: Cancer Drug Discovery and Development. Num Pages: 473 pages, biography. BIC Classification: MJCL. Category: (G) General (US: Trade). Dimension: 235 x 155 x 24. Weight in Grams: 724.
A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
Product Details
Format
Paperback
Publication date
2014
Publisher
Humana Press Inc. United States
Number of pages
473
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
460
Place of Publication
Totowa, NJ, United States
ISBN
9781627038164
SKU
V9781627038164
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Camptothecins in Cancer Therapy
"...an excellent all-around reference appropriate for researchers or clinicians in anticancer drug literature." - Doody's Health Science Book Review Journal