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Camptothecins in Cancer Therapy
. Ed(S): Burke, Thomas G.; Adams, Val R.
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Description for Camptothecins in Cancer Therapy
Hardback. A critical review of our understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. This work also discusses camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Editor(s): Burke, Thomas G.; Adams, Val R. Series: Cancer Drug Discovery and Development. Num Pages: 460 pages, biography. BIC Classification: MBGR; MJCL2; MMG; MNK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 31. Weight in Grams: 894.
A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.
Product Details
Format
Hardback
Publication date
2005
Publisher
Humana Press Inc. United States
Number of pages
460
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
460
Place of Publication
Totowa, NJ, United States
ISBN
9781588290274
SKU
V9781588290274
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Camptothecins in Cancer Therapy
"...an excellent all-around reference appropriate for researchers or clinicians in anticancer drug literature." - Doody's Health Science Book Review Journal