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Cancer Drug Resistance
Beverly A. . Ed(S): Teicher
€ 256.49
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Description for Cancer Drug Resistance
Hardback. Helps in understanding the complex interactions between host, tumor and cytotoxic or immunomodulatory agents. This work addresses the resistance of solid tumors to anticancer therapeutics by considering mechanisms that involve alterations in genetics and epigenetics, cellular biochemistry, and properties related to physiology of solid tumor mass. Editor(s): Teicher, Beverly A. Series: Cancer Drug Discovery and Development. Num Pages: 617 pages, biography. BIC Classification: MJCL; MMZR. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 28. Weight in Grams: 1144.
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are ... Read more
Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are ... Read more
Product Details
Format
Hardback
Publication date
2006
Publisher
Humana Press Inc. United States
Number of pages
617
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
617
Place of Publication
Totowa, NJ, United States
ISBN
9781588295309
SKU
V9781588295309
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Cancer Drug Resistance
"...a resource to scientists of diverse specialties with interests relating to the repsonse of malignant disease to current and experimental therapies." - Neoplasma "...an excellent book that is appropriate for scientists and clinicians with an interest in the basis of anticancer drug resistance." -Doody's Book Review, Weighted Numberical Score: 90 - 4 Stars!