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Concepts, Mechanisms, and New Targets for Chemotherapy
Franco M. . Ed(S): Muggia
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Description for Concepts, Mechanisms, and New Targets for Chemotherapy
Paperback. Editor(s): Muggia, Franco M. Series: Cancer Treatment and Research. Num Pages: 237 pages, biography. BIC Classification: MB; MJCL. Category: (G) General (US: Trade). Dimension: 235 x 155 x 13. Weight in Grams: 385.
Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity.
Modification of existing therapies based on the pursuit of leads arising from ... Read more
Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity.
Modification of existing therapies based on the pursuit of leads arising from ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer-Verlag New York Inc. United States
Number of pages
237
Condition
New
Series
Cancer Treatment and Research
Number of Pages
237
Place of Publication
New York, NY, United States
ISBN
9781461358299
SKU
V9781461358299
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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