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Cortico-subcortical Dynamics in Parkinson's Disease
Kuei-Yuan . Ed(S): Tseng
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Description for Cortico-subcortical Dynamics in Parkinson's Disease
Hardback. This book assembles all that is currently known about the pathophysiological changes underlying Parkinson's Disease (PD). It integrates key aspects of current PD knowledge and research, and provides critical reviews about mechanisms of neurodegeneration. Editor(s): Tseng, Kuei-Yuan. Series: Contemporary Neuroscience. Num Pages: 316 pages, 76 black & white illustrations, biography. BIC Classification: MJN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 1270.
The striatum is the principal input structure of the basal ganglia. Numerically, the great majority of neurons in the striatum are spiny projection neurons, which produce the inhibitory output of the striatum to the globus pallidum and substantia nigra. The major glutamatergic afferents to the striatum from the cerebral cortex make monosynaptic contact with spiny projection neurons. The dopaminergic afferents from the substantia nigra also synapse directly on the spiny projection neurons. Thus, the spiny projection neurons play a crucial role in the input–output operations of the striatum by integrating glutamatergic cortical inputs with dopaminergic inputs and producing the output ... Read more
The striatum is the principal input structure of the basal ganglia. Numerically, the great majority of neurons in the striatum are spiny projection neurons, which produce the inhibitory output of the striatum to the globus pallidum and substantia nigra. The major glutamatergic afferents to the striatum from the cerebral cortex make monosynaptic contact with spiny projection neurons. The dopaminergic afferents from the substantia nigra also synapse directly on the spiny projection neurons. Thus, the spiny projection neurons play a crucial role in the input–output operations of the striatum by integrating glutamatergic cortical inputs with dopaminergic inputs and producing the output ... Read more
Product Details
Format
Hardback
Publication date
2009
Publisher
Humana Press Inc. United States
Number of pages
316
Condition
New
Series
Contemporary Neuroscience
Number of Pages
316
Place of Publication
Totowa, NJ, United States
ISBN
9781603272513
SKU
V9781603272513
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-5
Reviews for Cortico-subcortical Dynamics in Parkinson's Disease
From the reviews: "This book nicely combines up-to-date basic science information with clinical data on one of the most prevalent movement disorders worldwide - Parkinson’s disease (PD). … Written for specialists in Parkinson’s disease, the book is appropriate for movement disorder neurologists, neurosurgeons involved in the surgical management of Parkinson’s, and basic scientists interested in the anatomy, physiology, ... Read more